平成30年度発足 新学術領域研究
発動分子科学

News&Event

研究成果 - C02-2

【原著論文】      【書籍/総説・解説】

原著論文
Error-suppression mechanism of PCR by blocker strands
H. Aoyanagi, S. Pigolotti, S. Ono, *S. Toyabe, Biophys J., 122, 1334-1341 (2023), DOI: 10.1016/j.bpj.2023.02.028

State transitions of a confined actomyosin system controlled through contractility and polymerization rate
R. Sakamoto, M. Miyazaki, and *Y. T. Maeda, Phys. Rev. Research, 5, 013208 (2023), DOI: 10.1103/PhysRevResearch.5.013208

Optimal Control of the F1-ATPase Molecular Motor
D. Gupta, S. J. Large, S. Toyabe, and *D. A. Sivak, J. Phys. Chem. Lett., 13, 11844–11849 (2022), DOI: 10.1021/acs.jpclett.2c03033

Morphological growth dynamics, mechanical stability, and active microtubule mechanics underlying spindle self-organization
T. Fukuyama, L. Yan, M. Tanaka, M. Yamaoka, K. Saito, S. C. Ti, C. C. Liao, K. C. Hsia, *Y. T. Maeda and *Y. Shimamoto, Proc. Natl. Acad. Sci. USA, 119, e2209053119 (2022), DOI: 10.1073/pnas.2209053119

Geometric trade-off between contractile force and viscous drag determines the actomyosin-based motility of a cell-sized droplet
R. Sakamoto, Z. Izri, Y. Shimamoto, M. Miyazaki and *Y. T. Maeda, Proc. Natl. Acad. Sci. USA, 119, e2121147119 (2022), DOI: 10.1073/pnas.2121147119

Collective motion of epithelial cells along a wrinkled 3D-buckled hydrogel
K. Shigeta, T. Fukuyama, R. Takahashi, K. Beppu, A. Tanaka and *Y. T. Maeda, RSC Adv., 12, 20174-20181 (2022), DOI: 10.1039/D2RA01768G

Negative autoregulation controls size scaling in confined gene expression reactions
*Y. T. Maeda, Sci. Rep., 12, 10516 (2022), DOI: 10.1038/s41598-022-14719-4

Exploring order in active turbulence: Geometric rule and pairing order transition in confined bacterial vortices
K. Beppu and *Y. T. Maeda, BPPB, 19, e190020 (2022), DOI: 10.2142/biophysico.bppb-v19.0020

Protein Needles Designed to Self-Assemble through Needle Tip Engineering
K. Kikuchi, T. Fukuyama, T. Uchihashi, T. Furuta, Y. T. Maeda, *T. Ueno, Small, 18, 2106401 (2022), DOI: 10.1002/smll.202106401

Controlling collective motion of kinesin-driven microtubules via patterning of topographic landscapes
S. Araki, K. Beppu, A. M. R. Kabir, *A. Kakugo, *Y. T. Maeda, Nano Letters, 21, 10478-10485 (2021), DOI: 10.1021/acs.nanolett.1c03952

Edge Current and Pairing Order Transition in Chiral Bacterial Vortices
K. Beppu, Z. Izri, T. Sato, Y. Yamanishi, Y. Sumino, Y. T. Maeda, Proc. Natl. Acad. Sci. USA, 118, e2107461118 (2021), DOI: 10.1073/pnas.2107461118

Phase Separation and Protein Partitioning in Compartmentalized Cell-Free Expression Reactions
S. Kato, D. Garenne, V. Noireaux, and Y. T. Maeda, Biomacromolecules, 22, 3451–3459 (2021), DOI: 10.1021/acs.biomac.1c00546

Cooperative stator assembly of bacterial flagellar motor mediated by rotation
KI. Ito, S. Nakamura, S. Toyabe, Nat. Commun., 12, 3218 (2021), DOI: 10.1038/s41467-021-23516-y.

Optimal rectification without forward-current suppression by biological molecular motor.
Y. Nakayama , S. Toyabe, Phys. Rev. Lett., 126, 208101 (2021), DOI: 10.1103/PhysRevLett.126.208101

Experimental characterization of autonomous heat engine based on minimal dynamical-system model
S. Toyabe, *Y. Izumida, Phys. Rev. Res E, 2, 033146 (2020), DOI: 10.1103/PhysRevResearch.2.033146

Harnessing random low Reynolds number flow for net migration
Takeru Morita, Toshiro Omori, Yohei Nakayama, Shoichi Toyabe, and *Takuji Ishikawa, Phys. Rev. E, 101, 063101 (2020), DOI: 10.1103/PhysRevE.101.063101

Tight chemomechanical coupling of the F1 motor relies on structural stability
Mana Tanaka, Tomohiro Kawakami, Tomoaki Okaniwa, Yohei Nakayama, Shoichi Toyabe, Hiroshi Ueno, and *Eiro Muneyuki, Biophys. J., 119 48-54 (2020), DOI: 10.1016/j.bpj.2020.04.039

Tug-of-war between actomyosin-driven antagonistic forces determines the positioning symmetry in cell-sized confinement
R. Sakamoto, M. Tanabe, T. Hiraiwa, K. Suzuki, S-I. Ishiwata, Y.T. Maeda and M. Miyazaki, Nat. Commun., 11, 3063 (2020), DOI: 10.1038/s41467-020-16677-9

Randomness and optimality in enhanced DNA ligation with crowding effects
T. Y. Shiraki, K. Kamei and *Y. T. Maeda, Phys. Rev. Research, 2, 013360 (2020), DOI:10.1103/PhysRevResearch.2.013360

Gene Expression in on-Chip Membrane-Bound Artificial Cells
Z. Izri, D. Garenne, V. Noireaux, Y. T. Maeda, ACS Synth. Biol.,8(8),267-278(2019),1705-1712 (2019), DOI: 10.1021/acssynbio.9b00247

Evaluation of the Duty Ratio of the Bacterial Flagellar Motor by Dynamic Load Control.
K. Sato, S. Nakamura, S. Kudo, *S. Toyabe, Biophys. J., 116,1952-1959 (2019), DOI: 10.1016/j.bpj.2019.04.004

Mechanically Distinct Microtubule Arrays Determine the Length and Force Response of the Meiotic Spindle
J. Takagi, R. Sakamoto, G. Shiratsuchi, Y. T. Maeda, *Y. Shimamoto
Developmental Cell, 49, 267-278(2019), DOI: 10.1016/j.devcel.2019.03.014

Cooperative ligation breaks sequence symmetry and stabilizes early molecular replication
S. Toyabe, *D. Braun, Phys. Rev. X, 9, 011056 (2019), DOI: 10.1103/PhysRevX.9.011056

書籍/総説・解説
“鋳型複製系における種の起源”
   鳥谷部 祥一, BRAUN Dieter, 生物物理 , 60, 295-299 (2020)

・“構成的アプローチで探る「発動する人工細胞」の設計原理”
   坂本遼太, 前多裕介, 化学と工業 , 73, 463-465 (2020)

Optothermal diffusiophoresis of soft biological matters: From physical principle to molecular manipulation
T. Fukuyama, *Y. T. Maeda, Biophys. Rev. , 12, 309-315 (2020), DOI: 10.1007/s12551-020-00692-7x

Efficiencies of molecular motors: a comprehensible overview
*C. B. Li and *S. Toyabe, Biophys. Rev. , 12, 419-423 (2020), DOI: 10.1007/s12551-020-00672-x

Session 2SDA—Nonequilibrium energetics of biological molecular machines
*S. Toyabe, C. B. Li, K. Kinbara, Biophys. Rev. , 12, 273-274 (2020), DOI: 10.1007/s12551-020-00634-3

“遊泳バクテリアで探るアクティブマターの秩序と制御”
   *前多裕介, 別府航早, 生物物理 , 60, 13-18 (2020), DOI: 10.2142/biophys.60.013

・“Geometric Effect for Biological Reactors and Biological Fluids”
   Kazusa Beppu, Ziane Izri, Yusuke T. Maeda*, Ryota Sakamoto,
   Bioengineering , 5, 110 (2018), DOI: 10.3390/bioengineering5040110

・“生体分子モーター ―進化が生んだ超高性能ナノマシン―”
   鳥谷部祥一, 精密工学会誌 , 11, 905-908 (2018), DOI: 10.2493/jjspe.84.905

Kinetic ratchet mechanism of ATP synthase circumvents rectification trade-off for inhibiting futile ATP consumption
Y. Nakayama, S. Toyabe, arXiv. , 2008, 07106 (2020)

Edge Current and Pairing Order Transition in Chiral Bacterial Vortex
K. Beppu, Z. Izri, T. Sato, Y. Yamanishi, Y. Sumino, Y. T. Maeda, arXiv. , 2002, 01247 (2020)

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